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刘德辉,梁秉中,黄丽仪,方月婵,郑景辉,汪帼斌,张世臣,林伟基,黄谭智媛,蔡启明,高永文.抗毒补肺汤预防SARS的临床观察[J].中国中西医结合杂志,2004,(8):685-688
抗毒补肺汤预防SARS的临床观察
Clinical Observation on the Preventive Effect of Kangdu Bufei Decoction on Acute Severe Respiratory Syndrome
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DOI:
中文关键词:  急性重症呼吸综合征(SARS)  中医药  预防  感冒
英文关键词:acute severe respiratory syndrome  traditional Chinese medicine  prevention  influenza
基金项目:
作者单位
刘德辉 香港中文大学流行病学及生物统计学中心 
梁秉中 香港中文大学中医中药研究所 
黄丽仪 香港中文大学中医中药研究所 
方月婵 香港中文大学中医中药研究所 
郑景辉 香港中文大学中医中药研究所 
汪帼斌 香港中文大学中医中药研究所 
张世臣 香港卫生署
香港中文大学化学病理学系 
林伟基 香港医药管理局 
黄谭智媛 香港医药管理局 
蔡启明 香港医药管理局 
高永文 香港医药管理局 
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中文摘要:
      目的观察抗毒补肺汤在急性重症呼吸综合征 (SARS)暴发期间对香港医务工作者的预防保护作用。方法在香港SARS肆虐期间 ,总共有 2 6 0 1名医务工作者接受了本研究中心派发的抗毒补肺汤 ,确信其中有 10 6 3名按要求连续 2周服用了该方药并寄回有效问卷 ,这部分人组成了中药组 ,另有未服本中药的 15 374名组成了对照组。通过这份问卷 ,可以了解受试者在研究开始的前 1天及第 14天、第 2 8天 ,其有关生活质量、感冒样症状、温病证候的变化。中药组有 37名接受了血清免疫学检验。结果中药组中无感染SARS者 ,而对照组中有 6 4名 (0 4 % )感染了SARS ,而且中药组自身前后对照 ,服药后在感冒样症状、温病证候、生活质量方面均得到显著改善。中药组 37份血清免疫学结果显示 ,服用中药后 ,机体免疫功能得到了改善与提高。结论抗毒补肺汤可能通过改善临床症状、提高生活质量及增强机体免疫功能来预防SARS的发生
英文摘要:
      ObjectiveTo observe the preventive protection of Kangdu Bufei Decoction (KBD) on acute severe respiratory syndrome (SARS) in medical personnel of Hong Kong at the epidemic period. MethodsAt the epidemic period of SARS in Hong Kong, there were 2 601 medical staffs administered with KBD distributed by the Center. It was confirmed that 1 063 persons had taken it for successive two weeks according to the request and returned the effective questionnaire, they were regarded as the TCM group. The control group was consisted of 15 374 subjects who didn’t take Chinese herbal medicine. Contents of the questionnaire including the condition of testee in terms of quality of life (QOL), changes of influenza like symptoms and Warm disease symptoms. Serum immunological examination had been conducted in 37 of the persons in the TCM group. ResultsNo one in the TCM group got SARS infection while in the control group, 64 (0 4%) had got. Self control before and after treatment examination showed that significant improvement appeared in the TCM in aspects of influenza like and Warm disease symptoms and QOL. The results of serum immunological examination showed that after administration of KBD, the immunity of organism was improved and elevated. ConclusionKBD could prevent the occurrence of SARS, it is possibly realized through improving symptoms, elevating QOL and enhancing immunity of organism.
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