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Effect of ear-acupoint pressing and Ear Apex (HX6,7) bloodletting on haemorheology in chloasma patients with Gan depression pattern

  • Acupuncture Research
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Chinese Journal of Integrative Medicine Aims and scope Submit manuscript

Abstract

Objective

To explore the therapeutical effect of ear-acupoint pressing combined with Ear Apex (HX6,7) bloodletting on haemorheology in chloasma patients with Gan (Liver) depression pattern.

Methods

A total of 180 chloasma patients were randomly assigned to three groups, 60 cases in each. Patients in the earacupuncture (EA) group were treated with ear-acupoint pressing combined with Ear Apex (HX6,7) bloodletting; vitamins C and E were put into practice in the Western medicine (WM) group together with 0.025% tretinoin cream for local external application; patients in the placebo group were treated with urea-cream by external use, while 30 healthy volunteers were in the control group. After a treatment course of 2 months, the changes of haemorheology, injury skin area, colour score and symptom score before and after the treatment were observed.

Results

There was no significant difference on whole blood reduced viscosity (high shear, medium shear, and low shear), erythrocyte aggregation index, hematocrit, plasma viscosity among the four groups (F =2.65, P>0.05). Compared with those before treatment, the whole blood viscosity (high shear) and whole blood reduced viscosity (high shear) after treatment in the EA group, the WM group and the placebo group were with no statistical significance (P>0.05). The injury skin area and colour score after treatment were significantly lower than those before treatment in the EA group and the WM group (P<0.05), while there was no significant difference in placebo group (P>0.05). Clinical symptoms of the EA group were obviously improved after the 2-month treatment, which was significantly different compared with those before treatment (P<0.05), there was significant difference compared with those of WM group and placebo group (P<0.05).

Conclusion

There was no significant difference on haemorheology index between healthy people and chloasma patients without angionosis, cerebrovascular disease, hematopathy, metabolic disease or any other organic disease. Ear-acupoint pressing combined with Ear Apex (HX6,7) bloodletting can effectively improve concurrent symptoms, lighten chloasma and lower chloasma area in patients accompanied by Gan depression.

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References

  1. Yu S, Yang FZ, Ma L. Dermatology and cosmetology. 1st ed. Beijing: Chinese Medicine Science and Technology Press; 1997:278–279.

    Google Scholar 

  2. Shi HF, Xu B, Guo XC, Qiu XW, Zhang YP, Ding XJ. Effect of Gan-Pi regulatory needling in treating chloasma. Chin J Integr Med 2010;16:66–70.

    Article  PubMed  Google Scholar 

  3. Chromatopsia Group, Committee of Chinese Association of Integrative Medicine of Dermatovenereology. Clinical diagnosis and efficacy standard of chloasma. Chin J Dermatovenereal (Chin) 2004;18:278.

    Google Scholar 

  4. Zheng XY, ed. Guiding principle of clinical research on new drugs of traditional Chinese medicine. 2nd ed. Beijing: Chinese Medicine Science and Technology Press; 2002:361–388.

    Google Scholar 

  5. Wang HT, ed. Cosmetology of traditional Chinese medicine. 1st ed. Beijing: China Press of Traditional Chinese Medicine; 1997:39–40.

  6. Cui ZJ, Cen Y. Status of research of chloasma. Sichuan Med J (Chin) 2004;25:116–118.

    Google Scholar 

  7. Zhang LP. Research advancement on etiology of cloasma. J Fujian Coll Tradit Chin Med (Chin) 2001;11:61–62.

    Google Scholar 

  8. Griffiths CE, Finkel LJ, Ditre CM, Hamilton TA, Ellis CN, Voorhees JJ. Topical tretinoin (retinoic acid) improves melasma. A vehicle-controlled, clinical trial. Br J Dermatol 1993;129:415–421.

    Article  PubMed  CAS  Google Scholar 

  9. Lu LH, Xu C, Li N. Professor Yang Jianbing’s experience in treating female’s chloasma faciei. Modern Tradit Chin Med (Chin) 2006;26:3–4.

    Google Scholar 

  10. Wang BC. Treatment on chloasma faciei from liver. Chin J Inform Tradit Chin Med (Chin) 2000;7:69.

    Google Scholar 

  11. Xiang YP, Ou YH. Talk about the relationships of psychic factors, neuropeptide and chloasma. Chin J Inform Tradit Chin Med (Chin) 2003;10:37–38.

    Google Scholar 

  12. Xia L, Min ZS. Advancement of treatment of traditional Chinese medicine and research on cloasma. Modern J Integr Tradit Chin West Med (Chin) 2005;14:1110–1111.

    Google Scholar 

  13. Xu CK, Chu FJ. The mechanism and syndrome differentiation of chloasma. J Liaoning Univ Tradit Chin Med (Chin) 2008;10:30–31.

    CAS  Google Scholar 

  14. Shi HF, Xu B. Clinical observation on the treatment of chloasma by Chinese herbs combined with acupuncture. Chin J Integr Med 2007;13:219–223.

    Article  PubMed  Google Scholar 

  15. Lin XY, Zhou GP, Li L. A preliminary analysis of serum enzymes and haemorheology for chloasma in female patients. J Clin Dermatol (Chin) 1997;26: 359–361.

    Google Scholar 

  16. Yan M, Qin ML, Xiao L. Haemorheology of cloasma. J Clin Dermatol (Chin) 1992;21:95.

    Google Scholar 

  17. Wang P. Skills of traditional Chinese medicine: ear-acupoint pressing. 1st ed. Tianjin: Tianjin Medicine Science and Technology Press; 1999:13.

    Google Scholar 

  18. Xing HY, Jin YJ, Zhu WY, Ma L, Li HM. Study on mechanism of hemorheological and cell ularheological property in hyperlipidemia. Chin J Microcircul (Chin) 2001;11:27–29.

    Google Scholar 

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Correspondence to Yan Shi  (石 焱).

Additional information

Supported by Zhejiang Province Science and Technology Project of Traditional Chinese Medicine (No. 2010B501678)

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Shi, Hf., Xu, F., Shi, Y. et al. Effect of ear-acupoint pressing and Ear Apex (HX6,7) bloodletting on haemorheology in chloasma patients with Gan depression pattern. Chin. J. Integr. Med. 22, 42–48 (2016). https://doi.org/10.1007/s11655-015-2109-2

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  • DOI: https://doi.org/10.1007/s11655-015-2109-2

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