中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

Author Name	Affiliation
Zong-chang Xie	Department of Traditional Chinese Medicine, Xiehe Hospital, Tongji Medical University, 430022, Wuhan
Zhen-kun Qian	Institute of Integrated Traditional Chinese Medicine and Western Medicine, Tongji Medical University, 430030, Wuhan
Zhong-wei Liu	Institute of Integrated Traditional Chinese Medicine and Western Medicine, Tongji Medical University, 430030, Wuhan

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Abstract:

The authors have investigated the effect of Radix Ginseng on peroxidation injury in myocardium and erythrocytes of streptozocin-induced diabetic rats. In the ginseng administered group (ginseng solution 0.2 g/200 g body weight once daily lasting 15??16 days), there was a significant decrease in the level of fasting blood glucose and lipid peroxide in myocardium and erythrocytes, in comparison with those of the model group (P<0.05). The superoxide dismutase activities in myocardium and erythrocytes of the ginseng group were increased (P<0.05), compared with those of the model group and the vitamin E treated group (vitamin E 10 mg/200 g??body weight once daily, lasting 15??16 days). The results suggest that the mechanisms of antiperoxidation injury of ginseng might include the following: (1) lowering the level of fasting blood glucose, decreasing monosaccharide auto-oxidation and partially protecting the production of free radicals; (2) elevating the activity of enzymatic free radical scavenger in cells, such as superoxide dismutase; and (3) directly eliminating the superfluous free radicals.