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Screening of anti-SIV drugs from Chinese medicinal herbs |
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Author Name | Affiliation | Chong-fen Guan | Institute of Basic Theory, China Academy of Traiditional Chinese Medicine, 100700, Beijing | Yi-zhe Wang | Institute of Basic Theory, China Academy of Traiditional Chinese Medicine, 100700, Beijing | Xiao-xian Wu | Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences, 100021, Beijing | Fu-qiu He | Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences, 100021, Beijing | Xin-ming Tu | Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences, 100021, Beijing |
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Abstract: |
The inhibitory activities of more than 40 species of Chinese medicinal herbs or their single chemical components against simian immunodeficiency virus (SIV) have been studied. The study revealed that four species of medicinal herbs and a single chemical component had a more than 50% inhibition effect on SIV antigen expression, and the inhibitory rate of five other herbs on SIV antigen expression was between 30%~50%. The results suggest Chinese medicinal herbs could inhibit SIV activity. |
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