中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

Author Name	Affiliation
Zhi-jian Yu	Digestive Disease Research Section, Affiliated Hospital of Nantong Medical College, 226001, Nantong
Xian-yong Meng	Digestive Disease Research Section, Affiliated Hospital of Nantong Medical College, 226001, Nantong
Ke-cheng Xu	Digestive Disease Research Section, Affiliated Hospital of Nantong Medical College, 226001, Nantong
Zheng-ju Ge	Digestive Disease Research Section, Affiliated Hospital of Nantong Medical College, 226001, Nantong

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Abstract:

Transcatheter arterial embolization with hydroxycamptothecine, cantharidin and cisplatin, thoroughly mixed with large doses of interferon and interleukin-2, was performed in 48 cases with unresectable intermediate or advanced hepatocellular carcinoma. The results demonstrate a partial remission rate of 54.2%, significantly higher than that in embolization with chemotherapeutic agents alone (cisplatin, adriamycin and mitomycin, 32.1%,P<0.01). Morever, the adverse reactions of hydroxycamptothecine and cantharidin, when applied systemically, including hematuria or urodynia were successfully eliminated.