中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

Author Name	Affiliation
Zhuang-lei Shen	Shangcheng District People’s Hospital, 310001, Hangzhou
Nai-ying Li	Department of Neurology, No. 2 Hospital of Zhejiang Medical University, China
Xiao-ping Ge	Shangchen District Hospital of TCM, Hangzhou
Xue-fan Chen	Shangcheng District People’s Hospital, 310001, Hangzhou
Wen-guo Zhao	Hangzhou Medical Radioimmunity and Testing Centre, China
Ru-mei Song	Laboratory of No. 1 Municipal Hospital, Hangzhou
Yong-hui Shen	The 4th People’s Hospital, Hangzhou

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Abstract:

Chronic renal failure patients (as test group) under treatment by Baoyuan Dahuang Decoction, other 20 cases (as control group) by western medicine, mainly coated aldehyde oxystain, had commonly blood urea nitrogen and creatinine decreased. But among the test group, the hemoglobin increased obviously, the symptons of fatigue, lassitude in loin and legs, lack of appetite, sexual disorder, and mental depression improved markedly (P<0.01), and estradiol, progesterone, testosterone as well as creatine phosphokinase were regulated notably compared with before treatment (P<0.01). Whereas in the control group, the symptoms were not significantly improved, hemoglobin, levels of sex hormones and creatine phosphokinase differed slightly. It is concluded that Baoyuan Dahuang Decoction possesses efficacy to improve chronic renal failure patients’ vitality and ability, the mechanism of which is related to anemia rectification and membrane function.