中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

Author Name	Affiliation
An-Tian Zhang	The Second Affiliated Hospital of Harbin Medical University, 150086, Harbin
Lin-Xue Qian	The Second Affiliated Hospital of Harbin Medical University, 150086, Harbin
Jing-Ming Guan	The Second Affiliated Hospital of Harbin Medical University, 150086, Harbin
Ya-Ju Du	The Second Affiliated Hospital of Harbin Medical University, 150086, Harbin
Zeng-Duo Wang	The Second Affiliated Hospital of Harbin Medical University, 150086, Harbin
Shao-Hua Li	The Second Affiliated Hospital of Harbin Medical University, 150086, Harbin
Hui-Chun Guo	The Second Affiliated Hospital of Harbin Medical University, 150086, Harbin

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Abstract:

One hundred and twenty-eight patients with active peptic ulcer were treated with Xilei powder for 4 weeks, their PGE₂ levels in both serum and gastro-duodenal mucosa were significantly higher than those before treatment (P<0.01). The rate of negative conversion of Helicobacter pylori (HP) showed in 63.3% of cases. The distributed density of HP significantly reduced (P<0.01). These results indicated that Xilei powder could heal ulcer probably owing to the increasing of the PGE₂ level in gastro-duodenal mucose, and inhibiting the growth and reproduction of HP so that to eliminate the HP, but did not owing to inhibit the gastric acid secretion and the release of gastrin.