中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

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Effect of Yuxintong capsule on serum creatine phosphokinase activity and plasma endothelin concentration in acute myocardial ischemic dogs) capsule on serum creatine phosphokinase activity and plasma endothelin concentration in acute myocardial ischemic dogs

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Author Name	Affiliation
Yan Lei	Xiyuan Hospital, China Academy of Traditional Chinese Medicine, 100091, Beijing
Ke-Ji Chen	Xiyuan Hospital, China Academy of Traditional Chinese Medicine, 100091, Beijing

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Abstract:

The protective effect of the traditional Chinese compound medicine Yuxingtong (YXT) in capsule form on the experimental acute myocardial ischemia formation has been studied in dogs. The plasma endothelin concentration and serum creatine phosphokinase activity were measured after coronary occlusion in different medication groups and compared with the saline control group. Results showed that YXT could significantly lowered the plasma endothelin concentration and the serum creatine phosphokinase activity, it suggested that both YXT and diltiazem have the similar protective effect on acute myocardial ischemia and necrosis in dogs.