中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

Author Name	Affiliation
Su-Dong Guan	Bengbu Medical College, 233003, Anhui
Min Ge	Bengbu Medical College, 233003, Anhui
Yong-Qin Han	Bengbu Medical College, 233003, Anhui
Gui-Lan Liu	Bengbu Medical College, 233003, Anhui

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Abstract:

By means of stimulating bilateral phrenic nerves in rabbits, the effect of Shengmai San (SMS) injection on function of normal and fatigue diaphragm was observed with the measuring of diaphragm evoked potential (DEP), and the analysis of the power spectrum of diaphragmatic electromyogram (EMGdi) at spontaneous breathing. The results were as follows: (1) After the adminstration of 2 ml/kg of SMS, amplitude of DEP, central frequency, and the high/low frequency ratio were markedly increased. (2) Injecting SMS 2 ml/kg in 30 minutes before injury could effectively get rid of diaphragmatic fatigue following electrical stimulation of the phrenic nerves. (3) Injecting SMS in 2 ml/kg after fatigue could enhance the recovery of the diaphragmatic fatigue.