中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

Author Name	Affiliation
Li-Jun Liu	Bethune International Peace Hospital, 050082, Shijiazhuang
Cheng-Jie Guo	Shaa’nxi College of TCM, Shijiazhuang
Xin-Ming Jiao	Shaa’nxi College of TCM, Shijiazhuang
Ke-Jing Yin	Shaa’nxi College of TCM, Shijiazhuang

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Abstract:

This experiment mainly describes the effects of acupuncture on immunologic function and histopathology of transplanted mammary cancer in mice. The results were as follows: In acupuncture group, NK cell activity and T-lymphocyte positive rate of acid α-naphthyl acetate esterase (ANAE) and lymphocyte transformation rate were all increased. Compared with the control group, there was a significant difference (P<0.01). The difference was insignificant when compared with normal group (P>0.05). Comparing the pathology grading of acupuncture group with control group, it showed marked difference in pathological section (P<0.01). Adenoid structure and the degree of lymphocytic infiltration also have marked difference between acupuncture and control group (P< 0.05). Less tumour volume in acupuncture group than in control group were observed (P<0.01). This indicated that acupuncture might increase the immunologic function of transplanted mammary cancer in mice and inhibit the growth of mammary cancer and enhance both differentiation level of mammary cancer cells and lymphocytic infiltration. Possibly acupuncture might reduce the malignancy of mammary cancer cells.