中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

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Study on effect of Baoyuan Qiangshen Tablet No. I in prolongating interval of hemodialysis in patients of renal disease in terminal stagein prolongating interval of hemodialysis in patients of renal disease in terminal stage

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Author Name	Affiliation
Bi-Jiang Zhu	Jiangsu Research Center of Nephrology -with TCM-WM, 212002, Jiangsu Zhenjiang
Yu-Sheng Li	Jiangsu Research Center of Nephrology -with TCM-WM, 212002, Jiangsu Zhenjiang

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Abstract:

Objective: To evaluate the effect of Baoyuan Qiangshen Tablet No. I (BYQS), a Chinese herbal medicine for reinforcing Kidney, activating circulation and eliminating evil Turbid factors, in prolongating interval of hemodialysis in patients of terminal stage of renal disease (TSRD).Methods: Twenty cases of TSRD were treated with BYQS combined with hemodialysis once every 5 days and the effect was observed and compared with control group treated with routine hemodialysis once every 3 days.Results: The increasing levels of serum creatinine, and blood urea nitrogen of BYQS group at dialysis interval were all lower than those of the control group (P < 0.01). After 3 months’ treatment, serum creatinine, blood urea nitrogen of BYQS group were lower than those before treatment, plasma albumin, lipoprotein, urine level of prostaglandin and anemia were all improved to various extent, but the creatinine clearance rate was unchanged. Conclusions: BYQS could prolong the interval and reduce the times of dialysis by way of regulating the lipid metabolic disorder, improving pathological change of kidney and protecting function of residual kidney unit. BYQS combined with hemodialysis is a good way of integrated traditional Chinese and Western medicine in treating TSRD.