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| Study on therapeutic effect of compound decoction of comcide in treating withdrawal reaction of heroin dependent rhesuses |
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| KeyWord:heroin dependent rhesuses, withdrawal therapy, compound decoction of Comcide |
| Author Name | Affiliation | | Xiaodong Zhang | Institute of Drug Dependent, Kunming Medical College, 650031, Kunming | | Xiaohong Guo | Institute of Drug Dependent, Kunming Medical College, 650031, Kunming | | Guili Xu | Institute of Drug Dependent, Kunming Medical College, 650031, Kunming | | Ling Guo | Institute of Drug Dependent, Kunming Medical College, 650031, Kunming | | Zhaojiu Zhang | Institute of Drug Dependent, Kunming Medical College, 650031, Kunming | | Yuncheng Hou | Institute of Drug Dependent, Kunming Medical College, 650031, Kunming | | Zhengxian Zhang | Institute of Drug Dependent, Kunming Medical College, 650031, Kunming | | Lanxi Song | Yunnan Provincial Institute of Materia Medica, china | | Qingyun Zeng | The First Affiliated Hospital of Kunming Medical College, china | | Jiaxiong Jiang | Institute of Drug Dependent, Kunming Medical College, 650031, Kunming |
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| Abstract: |
| Objective: To observe the therapeutic effect of compound decoction of Comcide (CDC), a traditional Chinese medicine (TCM) in treating the withdrawal reaction (WR) of heroin dependent rhesuses (HDR). Methods: To study therapeutic effects of CDC and methadone in treating WR of HDR models induced by administering of heroin. Through observing, comparing and evaluating the scores of all groups gained during the first 4 days when the WR was most severe. Results: CDC and methadone had the same therapeutic effects on WR of HDR. There were significant differences between the scores of CDC and methadone, and that of natural withdrawal, P<0.01; while there were insignificant difference between the scores of CDC and that of methadone, P>0.05. Conclusion: CDC had the therapeutic effect in treating WR of HDR. |
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