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| Observation on effect of Shenmai injection in treating patients of congestive heart failurein treating patients of congestive heart failure |
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| Author Name | Affiliation | | Zhihong Liu | Division of Cardio-Pulmonary Circulation of Fuwai Hospital, Chinese Academy of Medical Sciences, (100037), Beijing | | Xiansheng Cheng | Division of Cardio-Pulmonary Circulation of Fuwai Hospital, Chinese Academy of Medical Sciences, (100037), Beijing | | Chaoyang Zhang | Division of Cardio-Pulmonary Circulation of Fuwai Hospital, Chinese Academy of Medical Sciences, (100037), Beijing | | Yanfen Zhao | Division of Cardio-Pulmonary Circulation of Fuwai Hospital, Chinese Academy of Medical Sciences, (100037), Beijing | | Yun Zhang | Division of Cardio-Pulmonary Circulation of Fuwai Hospital, Chinese Academy of Medical Sciences, (100037), Beijing | | Xinhai Ni | Division of Cardio-Pulmonary Circulation of Fuwai Hospital, Chinese Academy of Medical Sciences, (100037), Beijing | | Baiping Chen | Division of Cardio-Pulmonary Circulation of Fuwai Hospital, Chinese Academy of Medical Sciences, (100037), Beijing |
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| Abstract: |
| Objective: To observe the clinical therapeutic effect of Shenmai Injection (SMI) in treating patients of congestive heart failure.Methods: Effect of 16 cases treated with either SMI or potassium magnesium aspartate was observed by randomized crossover method and compared.Results: By using SMI for 2 weeks, the patients’ left ventricular ejective fraction (LVEF) was increased from 29.5 ± 9.0 to 36.6 ± 10.2 (P < 0.05), the heart function of 68.75% patients was improved, no side effect or toxicity was observed. Potassium magnesium aspartate improved the heart function in 37. 50% patients only but showed no effect on LVEF.Conclusion: SMI is an effective and safe drug in treating patients with congestive heart failure. |
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