中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

Author Name	Affiliation
Guangxiang Hong	Jiangxi College of TCM, 330006, Nanchang
Yanping Zhang	Xiyuan Hospital of China Academy of TCM, China
Jingyao Huang	Jiangxi College of TCM, 330006, Nanchang
Wei Wang	Xiyuan Hospital of China Academy of TCM, China
Li Ma	Jiangxi Provincial Hospital of TCM, China
Fengda Zhao	The First Affiliated Hospital of Jiangxi Medical College, China
Xiguang Fan	The Second Affiliated Hospital of Jiangxi Medical College, China
Jianjian Chen	Nanchang Municipal Hospital of Integrated Traditional Chinese and Western Medicine, China

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Abstract:

Objective: To evaluate the therapeutic effect of Juanxiao Tablet (JXT) in treating asthma.Methods: Clinical observation on 447 cases of asthma was done in double- or single-blinded control method, and the therapeutic effect and safety of JXT were analysed. The effect of JXT in anti-asthma, expectorant, antisepsis, hypoxia tolerance was studied, and its acute and chronic toxicity was also examined.Results: The clinical control rate in patients treated with JXT was 38.2 %, the markedly effective rate 31.2% and the total effective rate 93.4 %, whereas in patients treated with Oleum Vitex Negundo, the respective rates were 13.3 %, 20.0 % and 68.5%. Results of pulmonary function and IgE measurement were consistent with clinical effect. Experimental study showed that JXT has the actions of anti-asthma, expectorant, antisepsis and hypoxia tolerance enhancement, with its LD₅₀(40.48 ± 5.17) g/kg.Conclusion: JXT is a new Chinese herbal preparation of good effect, with less toxic-side effect for asthma treatment.