|
| Effect of compound 962 capsule on liver lipid peroxidation and indexes of thymus gland and spleen in rats |
| |
| View Full Text View/Add Comment Download reader |
|
| KeyWord:traditional Chinese compound, aging,liver lipid peroxidation,thymus index, spleen inde |
| Author Name | Affiliation | | Jin Chu | Pharmacology Department, Beijing Key Laboratory for Brain Aging, Xuanwu Hospital of Capital University of Medical Science, 100053, Beijing | | Bin Li | Pharmacology Department, Beijing Key Laboratory for Brain Aging, Xuanwu Hospital of Capital University of Medical Science, 100053, Beijing | | Lin Li | Pharmacology Department, Beijing Key Laboratory for Brain Aging, Xuanwu Hospital of Capital University of Medical Science, 100053, Beijing | | Cuifei Ye | Pharmacology Department, Beijing Key Laboratory for Brain Aging, Xuanwu Hospital of Capital University of Medical Science, 100053, Beijing | | Huibo Liu | Pharmacology Department, Beijing Key Laboratory for Brain Aging, Xuanwu Hospital of Capital University of Medical Science, 100053, Beijing | | Shida He | Pharmacology Department, Beijing Key Laboratory for Brain Aging, Xuanwu Hospital of Capital University of Medical Science, 100053, Beijing |
|
| Hits: 1005 |
| Download times: 516 |
| Abstract: |
| Objective: To investigate the effect of compound 962 capsule (abbre. as 962) on liver lipid peroxidation and indexes of thymus and spleen in aged rats.Methods: Rats were divided into young control, aged model, Piracetam, 962 middle dose (0.9 g/kg) and high dose (1.8 g/kg) groups. All test drugs were administrated for 1 month by gastrogavage. The liver lipid peroxidation was determined by thiobarbituric (TBA) method. The thymus index and spleen index were determined by weighing method.Results: 962 (middle and high dose) attenuated liver lipid peroxidation, increased the thymus index of aged rats. There was no effect on spleen index in all drug-treated groups.Conclusion: 962 could decrease liver lipid peroxidation and increase thymus index. It suggested that 962 might be beneficial in retarding aging process. This study was funded by Scientific Committee of Beijing (No. 951890600) and State Ministry of Personnel(No.l998) |
| Close |
|
|
|
