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| Clinical observation on Chinese and western integrative medicine in treating repeatedly recurrent chronic pyelonephritis |
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| KeyWord:chronic pyelonephritis, repeated recurrence, Chinese and western integrative medicine, compound TCM recipe |
| Author Name | Affiliation | | Guang-xiu Sun M. D. | Division of Nephrology, Hebei Provincial People’s Hospital, No. 348 Heping Road, 050051, Shijiazhuang, Hebei Province | | Qing-jie Liu | Clinics of Xinhua Pharmaceutical Factory, China | | Wen-rong Zhang | Division of Nephrology, Hebei Provincial People’s Hospital, No. 348 Heping Road, 050051, Shijiazhuang, Hebei Province | | Rui-qin Zhang | Division of Nephrology, Hebei Provincial People’s Hospital, No. 348 Heping Road, 050051, Shijiazhuang, Hebei Province |
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| Abstract: |
| Objective: To explore the clinical efficacy of Chinese and western integrative medicine (TCM-WM) in treating repeatedly recurrent chronic pyelonephritis (CPN) and its therapeutic mechanism. Methods: Ninety-one repeatedly recurrent CPN patients were randomly divided into 2 groups, the control group (45 cases) treated with sufficient amount of sensitive antibiotics and other WM, the treated group (46 cases) treated with above-mentioned WM complemented with TCM syndrome differentiation (SD). Results: In the treated group completely cured was 14 cases (30.4%), markedly effective 14 cases (30.4%), the total effective rate was 91.3%; while that of the control group was 4 (8.9%), 5 (11.1%), and 48.9% respectively, (P<0.05) and (P<0.01); the mean days of urinary bacteria and urinary routine negative conversion were in the treated group 19.6±12.6 days and 24.3±11.5 days, obviously shorter than those of the control group (35.6±14.6 days and 53.6±16.4 days), P<0.01; the various symptoms of the treated group improved or disappeared in a short time, while in the control group a few patients improved in a longer period (P<0.01); the various immune parameters improved in the treated group, while in the control group only IgA was elevated to some extent (P<0.05), in comparing these data, the difference was significant (P<0.01). Conclusion: The TCM-WM integrative treatment could obviously raise the clinical efficacy, accelerate the symptom improvement, and enhance the immune function. |
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