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| Study on treatment of 313 patients with mid-late primary hepatocarcinoma by integrated traditional chinese and western medicine |
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| KeyWord:mid late primary hepatocarcinoma, integrated traditional Chinese and western medicine, prospective contrast study |
| Author Name | Affiliation | E-mail | | Chang-quan Ling | Department of TCM, Changhai Hospital Affiliated to Second Military Medical University, 200433, Shanghai | lingchangquan@hotmail.com | | Zhe Chen | Department of TCM, Changhai Hospital Affiliated to Second Military Medical University, 200433, Shanghai | | | De-zeng Zhu | Department of TCM, Changhai Hospital Affiliated to Second Military Medical University, 200433, Shanghai | | | Chao-qin Yu | Department of TCM, Changhai Hospital Affiliated to Second Military Medical University, 200433, Shanghai | | | Xue-qiang Huang | Department of TCM, Changhai Hospital Affiliated to Second Military Medical University, 200433, Shanghai | | | Xu-ying Wan | Department of TCM, Changhai Hospital Affiliated to Second Military Medical University, 200433, Shanghai | | | Jin Li | Department of TCM, Changhai Hospital Affiliated to Second Military Medical University, 200433, Shanghai | | | Jian Chen | Department of TCM, Changhai Hospital Affiliated to Second Military Medical University, 200433, Shanghai | | | Jian Shen | East Surgical Hospital of Liver and Gallbladder Affiliated to Second Military Medical University, China | | | Guang-shun Yang | East Surgical Hospital of Liver and Gallbladder Affiliated to Second Military Medical University, China | | | Meng-chao Wu | East Surgical Hospital of Liver and Gallbladder Affiliated to Second Military Medical University, China | |
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| Abstract: |
| To evaluate objectively the clinical effect and superiority of integrated traditional Chinese and western medicine (TCM-WM) in treating mid-late hepatocarcinoma.Methods: The 313 patients observed were divided randomly into 3 groups, Group Ⅰ, Ⅱ and Ⅲ, they were treated with protocol TACE, protocol PEI and comprehensive conservative therapy respectively. Each group was sub-divided into 2 sub-groups, sub-group A and B, and sub-group As was treated coordinately with different Chinese herbal medicine, Sisheng Decoction to sub-group ⅠA and ⅡA, and cinobufacin or norcantharidin to ⅢA respectively. And Chinese herbal medicine prescribed according to TCM Syndrome Differentiation was also given to all the sub-group As.Results: The integrated therapy showed significant effect in treating mid-late hepatocarcinoma, as it could improve significantly the clinical symptoms and signs, raise the quality of life and prolong the survival time in patients. When TCM-WM cooperated with TACE, it could alleviate the toxic effect and enhance the therapeutic effect of chemotherapy. There was statistical significant difference in clinical effect between the TCM-WM treated groups and the western medicine treated groups (P<0.05).Conclusion: TCM-WM therapy displays not only the action in enhancing the short-term therapeutic effect of treatment in treating mid-late hepatocarcinoma but also shows significant effect in enhancing long-term therapeutic effect and prolonging survival time in patients. It is worth further spreading. |
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