中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

Author Name	Affiliation	E-mail
Yan Zhao	Department of Senile Diseases, Xiyuan Hospital, China Academy of TCM, 100091, Beijing	quhh@amms. ac. cn
Wen-quan Zhou	Department of Senile Diseases, Xiyuan Hospital, China Academy of TCM, 100091, Beijing
Pu Gao	Department of Senile Diseases, Xiyuan Hospital, China Academy of TCM, 100091, Beijing
Ling Cui	Department of Senile Diseases, Xiyuan Hospital, China Academy of TCM, 100091, Beijing

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Abstract:

Objective

To assess the efficacy of Xianlong Capsule (XLC) in treating senile vascular dementia (VD).

Methods

Forty-six patients of VD were randomly divided into two groups. The patients in XLC group (n=24) were treated with XLC and the patients in the control group (n=22) were treated with Hydergine. The therapeutic effect on dementia, TCM Syndrome, neurofunction deficit score, activities of daily living (ADL) score, Hasegawa Dementia Score (HDS) and mini-mental state examination (MMSE), etc. were examined and compared before and after treatment.

Results

XLC could markedly increase MMSE scores and HDS of VD patients. It showed effect in ameliorating the TCM Syndromes and neurofunction deficit score significantly and could markedly improve the daily living activity of patients. The effect of XLC was better than that of Hydergine

Conclusion

XLC has definite effect in treating senile vascular dementia.