中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

Author Name	Affiliation	E-mail
Pu Meng	Pediatric Department of the Affiliated Union Hospital, Tongji University of Medicine, Tongji	zhangzhil9@263.net
Dong-Feng Zhou	Pediatric Department of the Affiliated Union Hospital, Tongji University of Medicine, Tongji
Ping Zhao	Pediatric Department of the Affiliated Union Hospital, Tongji University of Medicine, Tongji
Chuan-Xiong Xia	Pediatric Department of the Affiliated Union Hospital, Tongji University of Medicine, Tongji

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Abstract:

Objective

To find a method of treatment for correcting hyperbilirubinemia timely and effectively to prevent bilirubin induced cerebral damage in the newborn.

Methods

The newborns with hyperbilirubinemia in the treated group were treated with conventional treatment plus Butyribacterial preparation (BBP) and Simo Decoction (SMD, taken orally, and the effect was compared with that in control group A treated with conventional treatment only and that in control group B treated with conventional treatment plus BBP.

Results

The mean daily decreasing rate of bilirubin in the treated group was 51.11±25.03 μmol/L, which was higher than that in control groups A (39.36 + 22.44 μmol/L) and B (43.24±24.18 μmol/L), respectively (P<0.01 andP<0.05). The bilirubin decreasing value on the first day and the speed of bilirubin decreasing (to 102. 6 μmol/L) in the treated group were both higher than those in the control groups,P<0.01.

Conclusion

The combined therapy of conventional treatment plus BBP and SMD could rapidly reduce the blood bilirubin level in the newborn with hyperbilirubinemia, and shorten the therapeutic course markedly, and the therapeutic effect is superior to that of the conventional treatment alone or that of the conventional treatment plus BBP only.