中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

Author Name	Affiliation	E-mail
Xiao-xia Wu	Nanjing University of TCM, 210029, Nanjing	gzwxx@sina.com
Zhong-sheng Min	Institute of Dermatology, Peking Union Medical University, Chinese Academy of Medical Sciences, Peking
Wu-qing Zhou

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Abstract:

Objective

To study the effect of Yuyin recipe, a Chinese composite recipe, on cultured human epithelial cell proliferation in vitro

Methods

YYR in different concentrations was added separately into the keratinocyte CoLo-16 line, after the latter had been cultured 24 hrs, to be co-cultured for different periods of time (24–72 hrs). A blank control group was set up in the meantime. Effect of YYR with different concentrations and different acting time on keratinocyte proliferation was observed by MTT method

Results

YYR in different concentrations showed significant inhibitory effect on keratinocyte CoLo-16 line in concentration-dependent and acting-time-dependent manner

Conclusion

Inhibition on over proliferation of epithelial cells may be one of the mechanisms of YYR in curing psoriasis.