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Clinical observation on effect of Yishen Jiedu Recipe in retarding the course of chronic renal failurein retarding the course of chronic renal failure
  
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Author NameAffiliation
Shuang-hua Chen Guizhou Provincial Zunyi Hospital, 563002, Guizhou 
Zun-pu Ban Guizhou Provincial Zunyi Hospital, 563002, Guizhou 
Jian-lin Cao Guizhou Provincial Zunyi Hospital, 563002, Guizhou 
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Abstract:
      

Objective

To observe the effect of Yishen Jiedu Recipe (YSJDR) in retarding the course of chronic renal failure (CRF)

Methods

Forty-five patients were divided into two groups, the 22 patients in Group A were treated with low-protein diet and blood pressure controlling therapy only, while the 23 patients in Group B were treated with additional YSJDR. The time (month) for doubling serum creatinine (SCr) level was taken to evaluate the speed of CRF progression

Results

In Group A, the time for SCr increased from 288.4±96.7 μmol/L to 586.3±251.3 μmol/L was 16.7±5.1 months, while in Group B the time for SCr increased from 291.2±101.2 μmol/L to 589.6±257.5 μmol/L was 28.2±8.7 months. Comparison between the two groups showed significant difference (P<0.05 )

Conclusion

On the basis of low-protein diet and blood pressure controlling therapy, the additional treatment of YSJDR could markedly retard the progression speed of CRF
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