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| Clinical evaluation of integrative Chinese and western medicine in treating SARS |
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| KeyWord:integrative Chinese and western medicine, severe acute respiratory syndrome, therapy,T lymphocyte subsets |
| Author Name | Affiliation | E-mail | | Li Xiu-hui | Beijing You’an Hospital, Capital University of Medical Sciences, 100054, Beijing | lixiuhui@sohu.com | | Zhang Ke | Beijing You’an Hospital, Capital University of Medical Sciences, 100054, Beijing | | | Hu Jian-hua | Beijing You’an Hospital, Capital University of Medical Sciences, 100054, Beijing | | | Guo Xin-hui | Beijing You’an Hospital, Capital University of Medical Sciences, 100054, Beijing | | | Hu Zhong-jie | Beijing You’an Hospital, Capital University of Medical Sciences, 100054, Beijing | | | Yang Yu | Beijing You’an Hospital, Capital University of Medical Sciences, 100054, Beijing | | | Liang Lian-chun | Beijing You’an Hospital, Capital University of Medical Sciences, 100054, Beijing | |
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| Abstract: |
| Objective: To evaluate the effective treatment with integrative Chinese and western medicine (ICWM) of severe acute respiratory syndrome (SARS).Methods: The 65 cases of SARS patients were treated with ICWM and 37 cases with western medicine (WM) alone as the control in our hospital from March 11 to April 30, 2003. The results were analyzed, with T subset profile tested for all the 102 patients.Results: Sixty-five cases of SARS patients treated with ICWM included 52 mild cases of whom 51 cases were cured (98.1%) and no patient died. As to the 13 severe cases in this group, 9 were cured (69. 2%) and 2 died (15. 4%). Of the 37 cases treated with WM alone, 16 out of the 18 common cases were cured (88. 9%) and 10 out of the 19 severe cases were cured (52. 6%), with the other 9 died (47. 4%). Comparison between the two groups (P=0. 061) showed the difference was close to the value for statistical significance. But considering that the number of samples was small, more cases are needed for further study. The immune function examination: in cases of the common type, after ICWM treatment, CD4 + T lymphocytes were increased from 360±247 cell/mm3 to 563±479 cell/mm3 (P < 0.05). In the group treated with WM alone, CD4 + T lymphocytes were increased from 331±193 cell/mm3 to 772±354 cell/mm3 (P < 0.05). As to the severe cases after ICWM treatment, CD4 + T lymphocytes increased from 352±279 cell/mm3 to 525±490 cell/mm3 (P > 0.05). In the group of severe cases treated with WM alone, CD4 + T lymphocytes reduced from 229±69 cell/mm3 to 205±108 cell/mm3 (P > 0.05). While after ICWM treatment, CD4 + T lymphocytes were significantly higher than that of the group treated with WM alone (P < 0.05).Conclusion: Compared with the group treated with WM alone, ICWM can significantly improve the prognosis, reduce the mortality as well as improve the immune function of SARS patients. This work is supported by Clinical Study of Integrative Chinese and Western Medicine in Treating SARS (No. Jing Zhong Ke SARS-01) |
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