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| Therapeutic effect of Shenfu Injection on secondary aplastic anemia of tumor patients after chemotherapy |
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| KeyWord:Shenfu Injection secondary aplastic anemia therapeutic effect |
| Author Name | Affiliation | E-mail | | Pan Jing-xin | The Second Affiliated Hospital of Fujian Medical University, 362000, Fujian | abcpjx@msn.com | | Guo Yi-bin | Genetics Teaching Department, College of Medical Sciences, Sun Yat-sen University, Guangzhou | | | Guo Xi-zhe | The Second Affiliated Hospital of Fujian Medical University, 362000, Fujian | | | Guo Jian-xin | The Second Affiliated Hospital of Fujian Medical University, 362000, Fujian | | | Chen Yun-feng | The Second Affiliated Hospital of Fujian Medical University, 362000, Fujian | | | Wang Zhi-dong | The Second Affiliated Hospital of Fujian Medical University, 362000, Fujian | |
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| Abstract: |
| Objective: To explore the effect of Shenfu Injection, SFI) on the secondary aplastic anemia (AA) of tumor patients after chemotherapy (CT).Methods: The 15 cases of SFI treated group, 10 cases of control group, 25 cases of SFI + granulocyte-macrophage colony stimulating factor (GMCSF) treated group and the group of 23 GM-CSF-treated tumor cases of secondary AA after CT were compared, with their increasing rate and the rebound speed of neutrophil, platelet, bone marrow nucleated RBC, granulocyte, and megakaryocyte all being investigated.Results: The increasing rate and rebound speed of granulocyte, platelet, and the increasing rate of bone marrow nucleated RBC, granulocyte, megakaryocyte were obviously higher than those of the control, and the clinical manifestations were also obviously improved. The increasing rate of platelet, bone marrow nucleated RBC, megakaryocyte of the SFI + GM-CSF group were higher than those of the group which used GM-CSF alone, while the increasing rate of granulocyte in blood and bone marrow in both groups was similar.Conclusion: Significant efficacy was shown in SFI for the treatment of secondary AA of tumor patients after CT. |
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