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| Effects of integrative Chinese and Western medicine on arterial oxygen saturation in patients with severe acute respiratory syndrome |
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| KeyWord:severe acute respiratory syndrome arterial oxygen saturation integrative Chinese and Western medicine |
| Author Name | Affiliation | E-mail | | Liu Bao-yan | Clinical Evaluation Center, China Academy of TCM, China | liuby@mail.cintcm.ac.cn | | Hu Jing-qing | Clinical Evaluation Center, China Academy of TCM, China | | | Xie Yan-ming | Clinical Evaluation Center, China Academy of TCM, China | | | Weng Wei-liang | Xiyuan Hospital, China Academy of TCM, China | | | Wang Rong-bing | Beijing Municipal Ditan Hospital, China | | | Zhang Yan-ping | Xiyuan Hospital, China Academy of TCM, China | | | Li Xiu-hui | Beijing Municipal You’an Hospital, China | | | Zhang Ke | Beijing Municipal You’an Hospital, China | | | Ren Ai-ming | Beijing Friendship Hospital, China | | | Li Jun | 302 Hospital, PLA, China | | | Wang Bao-guo | Beijing Tiantan Hospital, China | | | Tang Xu-dong | Guang anmen Hospital, China Academy of TCM, China | | | Wang Wei-dong | Guang anmen Hospital, China Academy of TCM, China | | | Ni Qing | Guang anmen Hospital, China Academy of TCM, China | | | Zhang Jin-ping | Beijing Municipal Chest Hospital, China | | | Wu Hong-jin | Beijing Municipal Hospital of Integrative Traditional Chinese and Western Medicine, China | | | Zhou Wei | Wangjing Hospital, China Academy of TCM, China | | | Geng Zhi | Peking University, China | | | He Yang-bo | Peking University, China | | | Liang Zhi-wei | Guangdong Provincial Hospital of TCM, China | | | He Li-yun | Clinical Evaluation Center, China Academy of TCM, China | | | Gao Fan-zhu | Clinical Evaluation Center, China Academy of TCM, China | | | Peng Jin | Clinical Evaluation Center, China Academy of TCM, China | |
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| Abstract: |
| Objective: To evaluate the effects of treatment of integrative Chinese and Western medicine(ICWM) on arterial oxygen saturation (SaO2) in patients with severe acute respiratory syndrome (SARS). Methods:The non-randomized, controlled trial was conducted on 447 SARS patients treated synchronouslywith western conventional treatment (WM group, n = 171 ) alone and ICWM (ICWM group, n = 276). Thechanges of the cases with normal level (≥95 % ) or abnormal level (＜95 % ) SaO2 were observed dynamically. Results: In the 3rd-14th day of the therapeutic course, the percentage of patients with normal SaO2 in the ICWM group was higher than that in the WM group (OR = 0. 5178, P =0. 0038), and this tendency was more evident in patients of the severe type ( OR = 0.18, P = 0. 0001). However, the statistical significance of difference was only shown in patients for whom the ICWM treatment started in the early period after the onset (≤7 days after it, OR=0. 3803, P=0. 006), but not shown in those who received ICWM treatment later in the mid-late period of SARS (P＞0.05). Conclusion: ICWM treatment, particularly when it is used for inter vention in the early stage, is beneficial for maintaining normal SaO2 in SARS patients. |
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