中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

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Comparative observation on the effects of Radix Tripterygium hypoglaucum tablet and Tripterygium glycosides tablet in treating erosive oral lichen planus

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KeyWord:erosive oral lichen planus Radix Tripterygium hypoglaucum tablet Tripterygium glycosides tablet

Author Name	Affiliation	E-mail
Lin Li-mei	Department of Periodontal Diseases, Hospital of Stomatology, Shandong University, 250012, Jinan	llm2001@hotmail.com
Qi Xiang-min	Department of Periodontal Diseases, Hospital of Stomatology, Shandong University, 250012, Jinan

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Abstract:

Objective: To compare the therapeutic effects of Radix Tripterygium hypoglaucum tablet (THT) and Tripterygium glycosides tablet (TGT) in treating erosive oral lichen planus( EOLP). Methods: The patients were randomized into two groups, and they were treated with THT ( n = 47) or TGT ( n = 47), respectively. The therapeutic effects were evaluated after 3 months treatment. Results: For the patients of grade 1, the total efficacy in TGT group was 85.71%, compared with 52.38% in THT group, the efficacy was statistically greater in the group receiving TGT (P = 0. 043). However, for the patients of grade 2, the difference was not statistically significant (P = 0. 173). Conclusion: TGT is more effective in treating EOLP than THT for grade 1 patients. However, TGT is. not suitable for patients of child bearing age.