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| Preliminary study on treatment of partial androgen deficiency in aging males with Jingui Shenqi Pill |
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| KeyWord:Jingui Shenqi Pill partial androgen deficiency in aging male hormone |
| Author Name | Affiliation | E-mail | | Che Wen-jun | The First Hospital of Changzhou City, the 3rd Affiliated Hospital of Suzhou University, 213003, Jiangsu | erya_guo@hotmail.com | | He Xiao-zhou | The First Hospital of Changzhou City, the 3rd Affiliated Hospital of Suzhou University, 213003, Jiangsu | | | Jiang Jian-pin | The First Hospital of Changzhou City, the 3rd Affiliated Hospital of Suzhou University, 213003, Jiangsu | | | Cai Wen-yuan | The First Hospital of Changzhou City, the 3rd Affiliated Hospital of Suzhou University, 213003, Jiangsu | | | Xie Si-jie | The First Hospital of Changzhou City, the 3rd Affiliated Hospital of Suzhou University, 213003, Jiangsu | |
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| Abstract: |
| Objective: To observe the efficacy and safety of Jingui Shengqi Pill (JSP) in treating partial androgen deficiency in aging males (PADAM), and to explore the new approach in improving the quality of life in PADAM patients.Methods: Forty patients with PADAM were treated with JSP, the efficacy was evaluated with international index of erectile function (IIEF) scoring, PADAM questionnaire scoring, hormone, prostatic specific antigen (PSA), etc., and the data before treatment were compared with those after treatment in the same group.Results: After 3 months of treatment, PADAM scoring and IIEF scoring were all significantly improved. Symptoms regarding physical ability, vasomotion, and psychical and mental condition all got improved more markedly than symptoms regarding sexual hypofunction. The serum level of testosterone was 3.85 ±0.36 before treatment and 5.02 ±0.83 after treatmnet (P<0.05); luteinizing hormone of 7.33 ±2.14 and 4.84 ±1.43 (P<0.01), follicule-stimulating hormone of 10.22 ±4.48 and 6.47 ± 3.28 (P<0.01), respectively. The level of PSA failed to change significantly (1.94 ±0.55 and 2.06 ± 0. 47,P>0.05)Conclusion: JSP is effective and safe in treating PADAM, the mechanism of it is different from supplementing extrinsic androgen. It may have produced the effect by means of favorably regulating the condition of sex hormone to improve the balance of pituitary-sex gland axis, so it has more extensive clinical application. |
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