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| Thermodynamic study on antibacterial effect of different extracts from Radix Isatis |
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| KeyWord:Radix Isatis thermodynamics antibacterial effect |
| Author Name | Affiliation | E-mail | | Zhao Yan-ling | Institute of Chinese Materia Medica, The 302 Hospital of PLA, 100039, Beijing
Academy of Military Medical Science, China | zhao2855@263.net | | Qu Fen | Clinical Laboratory, the 302 Hospital of PLA, China | | | Xiao Xiao-he | Institute of Chinese Materia Medica, The 302 Hospital of PLA, 100039, Beijing | | | Liao Qing-wen | Institute of Chinese Materia Medica, The 302 Hospital of PLA, 100039, Beijing | | | Wang Jia-bo | Institute of Chinese Materia Medica, The 302 Hospital of PLA, 100039, Beijing | | | Ma Yong-gang | Institute of Chinese Materia Medica, The 302 Hospital of PLA, 100039, Beijing | | | Sun Yu-qi | Institute of Chinese Materia Medica, The 302 Hospital of PLA, 100039, Beijing | |
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| Abstract: |
| Objective: To study and analyze the antibacterial effects of different extracts from Radix Isatis. Methods: Staphylococcus aureus was used as the studied object in the experiment. Antibacterial effects of extracts from Radix Isatis were observed by thermocalrimetry on Staphylococcus aureus, together with common pharmacological experiments. Results: The total extract, ethyl acetate (EtOAc) extract, n-butylalcohol (nBuOH) extract, chloroform (CHCl_3) extract and petroleum (P.E.) extract had antiviral effects to some extent while the residue after extracting had no antibacterial activity. The potency of antiviral activity among them was as follows: nBuOH extract > EtOAc extract > CHCl_3 extract> total extract >P.E. extract. Conclusion: The antibacteriall effects of Radix Isatis were not limited to any active portion, showing that Radix Isatis exerts its antibacterial effects by cooperation of different active fractions in varied ways. |
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