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| Effect of Tiaozhi Yanggan Decoction (调脂养肝汤) in treating patients with non-alcoholic fatty liver |
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| KeyWord:non-alcoholic fatty liver Tiaozhi Yanggan decoction traditional Chinese medicine therapy efficacy assessment |
| Author Name | Affiliation | E-mail | | Can-li Gu | People’s Hospital of Ruyang County, Henan Province, 471200, China | gcl8007@163.com | | Yun-ke Zhang | The First Affiliated Hospital of Henan College of Traditional Chinese Medicine, China | | | Yue-xiao Fu | People’s Hospital of Ruyang County, Henan Province, 471200, China | | | Shao-feng Yang | People’s Hospital of Ruyang County, Henan Province, 471200, China | | | Xin-qiang Li | Traditional Chinese Medicine Hospital of Ruyang County, Henan Province, China | |
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| Abstract: |
| Objective To observe the clinical efficacy and safety of Tiaozhi Yanggan Decoction (调脂养肝汤, TZYGD) in treating non-alcoholic fatty liver. Methods One hundred and thirty-eight patients were enrolled and randomized into two groups according to the random number table in a ratio of 3:1, with 8 cases eventually dropping out. The symptoms, signs, liver function markers, blood lipids, iconographic indices and clinical comprehensive efficacy after a 12-week treatment course were assessed in 101 patients treated with TZYGD in the treated group and 29 patients treated with Thiola in the control group. Results The total effective rate in the treated group and the control group was 81.19% and 68.97%, respectively, showing a significant difference between the two groups with the former being significantly higher than the latter (P<0.05). Moreover, the improvements in the symptoms, signs, liver function, blood lipids and iconographic indices in the treated group were favorable with no serious adverse reactions. Conclusion TZYGD is effective and highly safe in treating non-alcoholic fatty liver. |
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