中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

Author Name	Affiliation	E-mail
Zi-xiao Wei	Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China	weizix@hotmail.com

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Abstract:

Diabetic peripheral neuropathy (DPN) is a common chronic complication in diabetic patients, closely correlated with the development of the disease and with poorly controlled glucose levels. The common clinical signs show paresthesia, mostly manifesting as multiple peripheral neuritis, such as having a chilly or causalgic feeling, anaesthesia, formication, and pain, etc. All the symptoms usually start from the four extremities. The abnormal sensations at the limbs manifest as hyperesthesia in the early stage; however, it will decrease or vanish in the later stages. Dyskinesia is not uncommon, seen as decreased tendon reflex or myoatrophy.