|
| Effect of emodin in suppressing acute rejection following liver allograft transplantation in rats |
| |
| View Full Text View/Add Comment Download reader |
|
| KeyWord:emodin liver transplantation acute allograft rejection apoptosis immuno-suppression |
| Author Name | Affiliation | E-mail | | Sheng-zhang Lin | Department of Hepatobiliary Surgery, First Affiliated Hospital of Medical College, Zhejiang University, Hangzhou, China
Department of General Surgery, Second Affiliated Hospital of Wenzhou Medical College, Wenzhou, 325027, China
Key Lab of Combined Multi-organ Transplantation, Ministry of Health, Hangzhou, Zhejiang, 310003, China | zysxswzsz@zju.edu.cn | | Hong-fei Tong | Department of General Surgery, Second Affiliated Hospital of Wenzhou Medical College, Wenzhou, 325027, China | | | Kang-jie Chen | Department of Hepatobiliary Surgery, First Affiliated Hospital of Medical College, Zhejiang University, Hangzhou, China
Key Lab of Combined Multi-organ Transplantation, Ministry of Health, Hangzhou, Zhejiang, 310003, China | | | He Jing | Department of General Surgery, Second Affiliated Hospital of Wenzhou Medical College, Wenzhou, 325027, China | | | Xiao Yang | Department of General Surgery, Second Affiliated Hospital of Wenzhou Medical College, Wenzhou, 325027, China | | | Shu-sen Zheng | Department of Hepatobiliary Surgery, First Affiliated Hospital of Medical College, Zhejiang University, Hangzhou, China
Key Lab of Combined Multi-organ Transplantation, Ministry of Health, Hangzhou, Zhejiang, 310003, China | |
|
| Hits: 1238 |
| Download times: 497 |
| Abstract: |
| Objective:To investigate the mechanism of action of emodin for suppressing acute allograft rejection in a rat model of liver transplantation.Methods:Brown Norway(BW) recipient rats of orthotopic liver transplantation(OLT) were divided into three groups,Group A receiving isografting(with BW rats as donor), Group B receiving allografting(with Lewis rats as donor),Group C receiving allografting and emodin treatment (50 mg/kg daily).They were sacrificed on day 7 of post-transplantation,and their hepatic histolo... |
| Close |
|
|
|
