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Effect and mechanism of panaxoside Rg1 on neovascularization in myocardial infarction rats
  
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KeyWord:ginsenoside Rg1  mTOR protein  collateral circulation  signal transduction  myocardial infarction  
Author NameAffiliationE-mail
Xiao-dong Wang Department of Cardiac Surgery, the First Affiliated Hospital, China Medical University, Shenyang, 110001, China  
Tian-xiang Gu Department of Cardiac Surgery, the First Affiliated Hospital, China Medical University, Shenyang, 110001, China wangxd1123@126.com 
En-yi Shi Department of Cardiac Surgery, the First Affiliated Hospital, China Medical University, Shenyang, 110001, China  
Chun-mao Lu Department of Cardiac Surgery, the First Affiliated Hospital, China Medical University, Shenyang, 110001, China  
Chun Wang Department of Cardiac Surgery, the First Affiliated Hospital, China Medical University, Shenyang, 110001, China  
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Abstract:
      Objective:To investigate the effects and mechanisms of panaxoside Rg1 on the new vessel formation in acute myocardial infarction(AMI) rats.Methods:The AMI model of male Sprague-Dawley(SD) rats was established,and rats were randomly divided into the AMI model group,the treatment group of panaxoside Rg1,the placebo group and the treatment group of panaxoside Rg1 plus rapamycin.Cardiac creatases were determined with 1 mL blood drawn from vena caudalis of the rats 48 h after the model was successfully made. Aft...
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