中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

Author Name	Affiliation	E-mail
Min Wu	China Academy of Chinese Medical Sciences, Beijing, 100053, China
Jie Wang	China Academy of Chinese Medical Sciences, Beijing, 100053, China	wangjie0133@yahoo.com.cn
Long-tao Liu	Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China

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Abstract:

Coptis Chinensis is a traditional Chinese medicine herb that has the effect of clearing heat and drying dampness,purging fire to eliminate toxin.Berberine is the main alkaloid of Coptis Chinensis,and recent researches showed that berberine had the effect of anti-atherosclerosis.This paper reviewed the anti-atherosclerosis mechanism of berberine,which may be related to regulating lipids,anti-inflammation, decompression,reducing blood sugar,and inhibiting vascular smooth muscle cell proliferation.