中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

Author Name	Affiliation	E-mail
Jian Liu	Department of Rheumatology, The First Affiliated Hospital of Anhui College of Traditional Chinese Medicine, Hefei, 230031, China	liujianahzy@yahoo.com.cn
Rui-lian Liu	Department of Rheumatology, The First Affiliated Hospital of Anhui College of Traditional Chinese Medicine, Hefei, 230031, China

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Abstract:

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease chiefly affecting synovial membranes of multiple joints. The clinical manifestations are highly variable. Besides joint affection, extra-articular manifestations always occur in RA patients, such as lung, blood vessel, heart, endocrine glands, hematological system, and nervous system affections. In addition to Western medicine therapy, Chinese medicine also plays a significant role in the treatment of RA with good efficacy and less adverse reactions. This paper summarizes the effects of Xinfeng Capsule (新风胶囊), a Chinese medicine, and the mechanisms of its action in ameliorating the extra-articular manifestations based on a series of clinical and experimental researches.