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Therapeutic Effects of Shenfu Injection (参附注射液) on Post-Cardiac Arrest Syndrome |
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KeyWord:cardiac arrest, post-cardiac arrest syndrome, Chinese medicine, Shenfu Injection |
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Abstract: |
Survival rates after cardiac arrest have not changed substantially over the past 5 decades. Post-cardiac arrest (CA) syndrome (PCAS) is the primary reason for the high mortality rate after successful restoration of spontaneous circulation (ROSC). Intravenous administration of Shenfu Injection (参附注射液, SFI) may attenuate post-CA myocardial dysfunction and cerebral injury, inhibit systemic ischemia/reperfusion responses, and treat underlying diseases. In this article, we reviewed the therapeutic effects of SFI in PCAS. SFI might be useful in the treatment of PCAS, incorporating the multi-link and multi-target advantages of Chinese medicine into PCAS management. Further experimental and clinical research to verify the therapeutic effects of SFI in PCAS is required. |
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