中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

Author Name	Affiliation	E-mail
LI Jian-jun	Department of Diagnosis of Chinese Medicine, School of Basic Medical Sciences, Beijing University of Chinese Medicine, Beijing (10029), China	ljjhebei@126.com
CHEN Xiang-mei,WEI Ri-bao

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Abstract:

Objective: To investigate the potential of renal pathological index as a differential diagnosis factor for Chinese medicine (CM) syndromes typing in IgA nephropathy (IgAN)1 Methods: A total of 1,016 patients with IgAN was recruited from November 2001 to November 2004. All the signs and symptoms including picture of the tongue and pulse tracings were collected1 All patients were typed according to the CM syndrome typing scheme for chronic primary glomerulopathy. The severity of glomerulus and tubulointerstitial lesions (mild, moderate-severe) were evaluated using lee's grading system and the Katafuchi score system. Results: The syndrome types transform in turn by de?ciency of both the Spleen (Pi) and Lung (Fei) qi, de?ciency of both qi and yin, de?ciency of Liver (Gan) and Kidney (Shen) yin and deficiency of Spleen-Kidney (Shen) yang, with the aggravation of pathogenetic condition and that the manifestation of deficiency of qi clinically showed proliferative lesion of glomerular mesangium, while the glomerular sclerosis pathologically showed the manifestation of yin de?ciency. Conclusion: Renal pathological ?ndings may be a candidate of objective factors to re?ne CM syndrome typing process.