中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

In the field of life sciences, although system biology and "precision medicine" introduce some complex scientific methods and techniques, it is still based on the "analysis–reconstruction" of reductionist theory as a whole. Adaptability of complex system increase system behaviour uncertainty as well as the difficulties of precise identification and control. It also put systems biology research into trouble. To grasp the behaviour and characteristics of organism fundamentally, systems biology has to abandon the "analysis–reconstruction" concept. In accordance with the guidelines of complexity science, systems biology should build organism model from holistic level, just like the Chinese medicine did in dealing with human body and disease. When we study the living body from the holistic level, we will find the adaptability of complex system is not the obstacle that increases the difficulty of problem solving. It is the "exceptional", "right-hand man" that helping us to deal with the complexity of life more effectively.