中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

Author Name	Affiliation	E-mail
HE Xu-feng, PAN Wei-dong, YAO Yi-li
ZHANG Hui-min	Department of Dermatology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai (201203), China	happy2003_1@msn.com

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Abstract:

The histamine receptor antagonists in the treatment of allergic disease have limitations. The treatments of Chinese herbs have some curative effects on allergic skin lesions. Present research indicates that the mitogen-activated protein kinase (MAPK) signaling pathway might be equally important in allergic reactions. It was found that the inhibition of MAPK signaling pathways might relieve allergy symptoms, and some herbs can inhibit the MAPK pathway, which yields anti-allergy effects. Chinese medicines (CMs) have immense potential in the development of treatments for allergic disease.