中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

Author Name	Affiliation	E-mail
Usman Ali, Evhy Apryani, Muhammad Zaeem Ahsan
WANG Yong-xiang	King's Lab, Shanghai Jiao Tong University School of Pharmacy, Shanghai (200240), China	yxwang@sjtu.edu.cn

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Abstract:

Opioid drugs are the first line of defense in severe pain but the adverse effects associated with opioids are considered as a serious issue worldwide. Acupuncture/electroacupuncture is a type of Chinese medicine therapy which is an effective analgesic therapy, well documented in animals and human studies. Electroacupuncture stimulation could release endogenous opioid peptides causing analgesia in a variety of pain models. It can be used as an alternative therapy to control the opioid crisis.