中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

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Low-Frequency Magnetic Stimulation of Shenmen Acupoint Reduces Blood Oxygen Levels in Prefrontal Cortex of Healthy Subjects: A Near-Infrared Brain Functional Imaging Study

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KeyWord:Shenmen acupoint, transcranial magnetic stimulation, functional near-infrared spectroscopy, prefrontal lobe, healthy subjects

Author Name	Affiliation	E-mail
YUAN Jie, ZHENG Zhong, CAO Yue
LEI Ya-ling	Department of Encephalopathy, Shaanxi Provincial Hospital of Traditional Chinese Medicine, Xi'an (710003), China	624552101@qq.com

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Abstract:

Objective: To explore the effect of low-frequency magnetic stimulation at Shenmen (HT 7) acupoint on blood oxygen levels in the prefrontal cortex of healthy subjects. Methods: Functional near-infrared spectroscopy (fNIRS) technology was used to collect real-time data of oxygenated hemoglobin (oxy-Hb) in the prefrontal cortex of 16 healthy subjects at resting state and low-frequency magnetic stimulation of Shenmen. The mean and integral values of blood oxygen concentration were analyzed. Results: Compared with the resting state, the mean and integral values of blood oxygen concentration decreased during the task period, recovery period, and the whole process in the magnetic stimulation of Shenmen acupoint (P<0.05). In particular, the difference was statistically significant in the recovery period (P<0.01). Conclusions: The prefrontal cortex was widely activated and produced an immediate effect by reducing the local blood oxygen concentration at low frequency magnetic stimulation of Shenmen acupoint, which verifies the sedative effect of Shenmen acupoint.