中国结合医学杂志（英文版）Chinese Journal of Integrative Medicine

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Tumor interstitial fluid and postoperative recurrence of tumors: An experimental study for verifying hypothesis of “tumor-phlegm microenvironment”

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Author Name	Affiliation	E-mail
Da-zhi Sun	Department of Traditional Chinese Medicine, Shanghai Changzheng Hospital, the Second Military Medical University, Shanghai, 20003, China
Da-wei Ju	Department of Traditional Chinese Medicine, Shanghai Changzheng Hospital, the Second Military Medical University, Shanghai, 20003, China
Jin He	Department of Laboratory Digniostics, Shanghai Changzheng Hospital, the Second Military Medical University, Shanghai, 20003, China
Ye Lu	Department of Traditional Chinese Medicine, Shanghai Changzheng Hospital, the Second Military Medical University, Shanghai, 20003, China
Feng Wu	Department of Traditional Chinese Medicine, Shanghai Changzheng Hospital, the Second Military Medical University, Shanghai, 20003, China
Chang Li	Department of Pathology, Shanghai Changzheng Hospital, the Second Military Medical University, Shanghai, 20003, China
Pin-kang Wei	Department of Traditional Chinese Medicine, Shanghai Changzheng Hospital, the Second Military Medical University, Shanghai, 20003, China	changzhengzyk@163.com

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Abstract:

Objective

To explore a method of extracting tumor interstitial fluid (TIF) which is similar to muddy phlegm in Chinese medicine (CM), interleukin-8 (IL-8) in concentration was taken as the representative of the content of TIF, analyzed in the extracted TIF and the original tumor tissue, and examined to see whether TIF has an interfering effect on tumor recurrence.