宽胸气雾剂中止心绞痛发作速效作用的观察

作者	单位
郭士魁	中医研究院西苑医院心血管病研究室、药理组
陈可冀	中医研究院西苑医院心血管病研究室、药理组
钱振淮	中医研究院西苑医院心血管病研究室、药理组
翁维良	中医研究院西苑医院心血管病研究室、药理组
张问渠	中医研究院西苑医院心血管病研究室、药理组
李连达	中医研究院西苑医院心血管病研究室、药理组
徐铭渔	中医研究院西苑医院心血管病研究室、药理组

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中文摘要:

临床上由于很多冠心病心绞痛病人有"寒邪滞留经脉"、"胸阳不足"及"心阳不宣"的表现,所以,应用芳香温通治法足比较适宜的。宽胸气雾剂就是根据中医芳香温通这一治则制定的由细辛、良姜、荜拨、檀香、冰片等五味药组成的方剂,剂量比例为0.5:1.5:3.0:1.5:0.8,提取挥发油后制成气雾剂,以 F¹²为抛射剂。心绞痛发作时,瓶体倒立,对准口腔,喷射

英文摘要:

Kuan-Xiong aerosol are made of Volatiles of Asarum sieboldi(细辛),Alpinea officinarum(良姜),Piper longum(荜拨),Santalum album(檀香)and Dryobalanopsaromatica(冰片).In treating coronary anginal attacks, the authors of this paper made observations on 317 cases totalling 2,924 times and found the effective rate ranging between 47.60-58.07%(terminating the pain within 3 min.). In 16 cases,327 times,the authors made a further comparison between this aerosol and nitroglycerine (manufactured both at home and abroad),the effective rates being 50.06%,41.9% and 56.4% respectively (P>0.05). Experimental studies showed that this aerosol can relieve the vascular spasm in rabbits and dogs.The authors stress that such an evident effect should not be neglected.

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