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焦东海,刘训初,章启尧,马玉华,舒鸿年,胡希强,刘春堂,戴鸣鲸,华宝芬,高雅萍,杜宝金,朱新民,沈学敏,朱长民,施维智,庄德润,宋竹均,钱耀贤,林家宝,杜上鉴,戴克逊,李东园,陈均鸿.单味大黄治疗三种消化道急症1,000例的临床小结[J].中国中西医结合杂志,1982,(2):85-87,66,67
单味大黄治疗三种消化道急症1,000例的临床小结
Réumé of 1,000 Emergency Cases of Three Kinds of Digestive Tract Diseases Treated with A Single Recipe of Rhubarb
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DOI:
中文关键词:  生大黄粉  急性胰腺炎  急性胆囊炎  急性上消化道出血  治疗方法  有效率  止血时间  急症  白细胞总数  辨证论治
英文关键词:
基金项目:
作者单位
焦东海 上海市卢湾区中心医院 
刘训初 上海市卢湾区中心医院 
章启尧 上海市卢湾区中心医院 
马玉华 上海市卢湾区中心医院 
舒鸿年 上海市卢湾区中心医院 
胡希强 上海市卢湾区中心医院 
刘春堂 上海市卢湾区中心医院 
戴鸣鲸 上海市卢湾区中心医院 
华宝芬 上海市卢湾区中心医院 
高雅萍 上海市卢湾区中心医院 
杜宝金 上海市卢湾区中心医院 
朱新民 上海市卢湾区中心医院 
沈学敏 上海市卢湾区中心医院 
朱长民 上海市卢湾区中心医院 
施维智 上海市卢湾区中心医院 
庄德润 上海市卢湾区打浦桥地段医院 
宋竹均 上海市卢湾区顺昌路地段医院 
钱耀贤 上海第一医学院 
林家宝 上海第一医学院 
杜上鉴 上海医药工业研究院 
戴克逊 上海医药工业研究院 
李东园 上海医药工业研究院 
陈均鸿 上海医药工业研究院 
摘要点击次数: 1730
全文下载次数: 1103
中文摘要:
      五年多来,我们在用现代医学明确诊断的前提下,以病理学与药理学为依据进行辨证论治,不断精简复方药味,终于取得了用单味大黄治疗急性上消化道出血(肝硬化引起者除外)、急性胰腺炎(水肿型)与急性胆囊炎共1000例的较好疗效,符合"廉、简、验、便"的原则。现小结如下:资料分析
英文摘要:
      During the recent five years,a single recipe of rhubarb was used in the treatment of 1,000 cases of acute upper digestive tract bleeding(excluding cirrhosis of the liver),pancreatitis(edematous type)and cholecystitis. 1.Acute upper digestive tract bleeding:890 cases(79% male)in all.57% were duodenal ulcer complicated by bleeding.The rest was 20 other diseases including gastritis.Profuse bleeding occurred in 8%.After admission no patient was allowed any hemostat,except fluid replacement or blood transfusion in cases with profuse bleeding.A single recipe of rhubarb in powder, tablets or syrup was given in a dose of 3g 3 times per day until bleeding ceased in an average period of two days,which resulted in an effective rate of 97%.A random comparison was also tried between the use of rhubarb singly and the combined treatment of western medicine and Chinese medicinal herbs.Furthermore,the therapeutic effect in hemostatic process among six different preparations of rhubarb was also observed.The results showed that the use of rhubarb singly took the shortest time for arresting bleeding and absorption fever.It also had the merits of being cheap,convenient,and quick to recover.Owing to the differences in varieties and preparations of rhubarb,different therapeutic effects and side effects were also observed.At present it is assumed that the hemóstatic mechanism of rhubarb may be due to its local astringent of the tannic acid content and the constriction in local blood vessels. 2.Acute pancreatitis and cholecystitis:In 100 cases’of acute pancreatitis of winch 61% are female,abdominal pain was found in all cases,nausea and vomiting in 73 cases,fever in 74 cases,and jaundice in 8 cases,WBC count above 10,000 in 54 cases(of which 11 cases above 20,000),urine amylase over 1024u in 51 cases,and complication with other diseases in 29 cases. During the treatment,decompression of the gastrointestinal tract and fasting were not used,but a reasonable replacememt of fluid by infusion was allowed.A decoction of raw rhubarb singly of 30-60g each time and 5-10 times per day was given until recovery.In 17 cases of high fever above 39℃ or a white blood cell count over 20,000 or other complications,chloromycetin or other antibiotics was added The therapeutic effect was 100%.On the average the urine amylase waslowered down to normalin 2 days,the abdominal pain disappeared in 3 days,and jaundice and fever in 5 days.The average dose of rhubarb was altogether 450g for each case.It was reported that rhubarb has inhibitive effects on trypsin,lipase and amylase.This may be the chief mechanism in the treatment of acute pancreatitis.The same is also true of the treatment of acute cholecystitis in 10 cases.On the average it took 3 days to achieve basic recovery,In the literature rhubarb is known to have cholagogic antiphlogistic and other effects.This may be its chief mechanism in the treatment of acute cholecystitis.
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