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熊鉴然,周舒,陈海云,杨连兴.弦脉与血液动力学关系的实验研究[J].中国中西医结合杂志,1982,(3):172-175,133
弦脉与血液动力学关系的实验研究
An Experimental Study of Taut Pulse and Its Relation to Hemodynamics in Dogs
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DOI:
中文关键词:  血液动力学  脉波图  弦脉  股动脉  实验研究  动脉压力  周围血管  去甲肾上腺素  总阻力  脉象
英文关键词:
基金项目:
作者单位
熊鉴然 中国医学科学院基础医学研究所 
周舒 中国医学科学院基础医学研究所 
陈海云 中国医学科学院基础医学研究所 
杨连兴 中国医学科学院基础医学研究所 
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中文摘要:
      弦脉是临床最常见脉象之一,各地用脉波图法研究脉象以弦脉最多,对其脉波特点的认识比较一致,对其产生机理也有一定了解。我们在临床实验的基础上,复制了类似于人平脉、弦脉脉波的狗实验图形,探讨了它们与血液动力学的相互关系,以期为研究病理情况下脉波的规律及机制打下基础。材料与方法一、实验动物:健康杂种狗6条,雌雄皆有,体重11.5~16(平均13.7)kg。二、测试方法:用固态压力传感器,以相当于
英文摘要:
      A tracing method was established to reproduce pressure pulse-waves in dogs.Taut pulse was reproduced with intravenous drip of 1mg% noradrenaline solution at the rate of 5-10gt.per minute,and smooth pulse was achieved with an infusion of 6% dextran(molecular weight 45,000-95,000)about 15ml/kg body weight.The interrelation between the taut pulse and hemodynamics was studied.It was observed that cubital pulse-waves varied in form with the changes of hemodynamic factors, principally the total systemic vascular resistance(TSVR).The parameters of pulse-waves and hemodynamic indexes determined simultaneously were analysed by means of computer.It has been demonstrated that the appearance of taut pulse is related significantly to the increment of TSVR and/or cardiac output,and the appearance of smooth pulse to the increase in blood volume of circulation,cardiac output and reduction in TSVR.However,the changes of the pulse-wave are related more closely to the integration of hemodynamics.
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