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王学斌,张纪祥,邓书礼,吴人川,唐有元.黄杨宁治疗冠心病546例临床观察[J].中国中西医结合杂志,1982,(4):216-217,195
黄杨宁治疗冠心病546例临床观察
A Clinical Observation on 546 Cases of Coronary Heart Disease Treated with Cyclovirobuxine D
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DOI:
中文关键词:  黄杨宁  临床观察  隐性冠心病  治疗前后  心绞痛  药理试验  快速心律失常  皖南地区  显著差异  抗心律失常
英文关键词:
基金项目:
作者单位
王学斌 南京军区空军后勤卫生处 
张纪祥 南京军区空军后勤卫生处 
邓书礼 南京军区空军后勤卫生处 
吴人川 南京军区空军后勤卫生处 
唐有元 南京军区空军后勤卫生处 
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中文摘要:
      黄杨宁——环常绿黄杨硷 D(cyclovirobuxineD),是从小叶黄杨中提取的有效单体,近几年来根据药理试验和临床应用,证明具有治疗冠心病及抗心律失常的作用。自1979年3月至1980年7月分别在上海、南京、浙江、皖南地区部分医院进行了验证,现将546例临床观察报告如下:
英文摘要:
      Cyclovlrobuxine D is a kind of active constituent extracted from Chinese Buxus microphylla Sieb et Zucc.var.sinica Rehd.et Wils.In recent years,pharmacologic tests and clinical applications have proved that it can be used to treat coronary heart disease and cardiac arrhythmia.The analysis of these cases are as follows: Cyclovirobuxine D has anti-angina effect.But of 360 cases of angina pectoris,it was effective in 323 cases having a curative rate of 89.7%.Among 146 cases of the classified groups,it was effective in 44 cases(88%)in the mild angina pectoris group(50 cases),55 cases(94%)in the moderate group(58 cases),and 36 cases(95%)in the severe group(38 cases).Evidently the curative effect on the severe group was the best of the three. Among499 cases of the improved electrocardiogram,it was effective in 150 cases,having a curative rate of 30%,and 182 cases were improved(36.5%).This amounts to a total of 332 cases with a curative rate of 66.5%.This is obviously higher than those of the comparative groups. Cyclovirobuxine D has an obvious action against cardiac arrhythmia,particularly ventdcular extrasystole.Out of 115 cases ofarrhythmia in the above group,it was effective in 51 cases with a curative rate of 44.3%;33 cases were improved(28.7%);and 31 cases were ineffective(27.0%).This amounts to a total of 84 cases with a curative rate of 73.0%.
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