气功及降压药治疗高血压426例疗效和血浆多巴胺-β-羟化酶活性变化

The Efficacy of Qigong(Breathing Exercise)and Antihypertensive Drug Treatment in 426 Hypertensive Patients and the Change of Plasma Dopamine-β-Hydroxylase Activity

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中文关键词: 高血压分期活性变化气功疗法高血压病人多巴胺血浆临床观察临床疗效气功锻炼变化幅度

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作者	单位
王崇行	上海市高血压研究所
尤传一	上海市高血压研究所
赵光胜	上海市高血压研究所
徐定海	上海市高血压研究所
李迪元	上海市高血压研究所
钱岳晟	上海市高血压研究所
邝安堃	上海市高血压研究所

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中文摘要:

二十多年来,用现代科学方法对气功在高血压病中的临床疗效和作用原理的研究揭示,气功对降低血压、稳定血压、巩固疗效确有实效,气功锻炼对机体内部机能具有多方面的积极调整作用。为了普及和推广气功疗法,我们在实践基础上吸取各家所长,整理修订了以心静体松、动静结合为要领的高血压基本功法,并用于门诊基层防治实践,现将临床观察及实验结果报道如下。

英文摘要:

Clinical and experimental studies on Qigong(气功,breathing exercise)treatment for hypertension indicate that breathing exercise may actively regulate the internal function of human body,and its efficacy in the treatment of hypertension may be claimed as reliable. 426 hypertensives under uninterrupted and consistent medication were divided into two groups.The first is the Qigong group (304 cases),i:e.,Qigong with regulatory medication,which was followed up for one year.This group had a total effective rate of 86.2%,among which the rate of marked efficacy was 42.5%.The control group(122 cases)with regulatory medication only was also followed up for one year.However,its total effective rate and the rate of marked efficacy were 67.2% and 22.5% respectively. This indicates that the efficacies for these two groups do differ significantly(P<0.01). Many experimental data suggest that plasma dopamine-β-hydroxylase(DβH)activity may reflect the sympathetic nervous function.26 hypertensives(2nd stage)with breathing exercise over one year were investigated for their plasma DβH activity by means of cross-over and self-control after and before breathing cxercise and rest.DβH activity before breathing exercise and restis 19.71±1.47 IU(mean±SEM)and 19.29±1.47 IU respectively.It decreases by 1.47±0.69 IU after breathing exercise but increases by 0.57±0.66 IU after rest.The difference between the values of change of plasma activity after and before breathing exercise is statistically significant(P<0.05).However,the difference between the values after and before rest is relatively insignificant(P>0.05).The differences of the absolute values of change,or,between the percentages of change of DβH activityin the two groups are both statistically significant(P<0.05).It is suggested that breathing exercise cart reduce the excitability of sympathetic nervous activity and regulate the function of unbalanced autonomous nervous system.

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