甘草水煎剂对应激状态下小鼠腹腔巨噬细胞吞噬功能的影响

近年来,一些研究者从免疫学角度探讨了中医方药对单核吞噬细胞系统的影响,发现许多方药(特别是某些具有补益作用的方药)能够促进巨噬细胞的吞噬能力,提高机体的非特异性免疫功能。但从应激学说的角度,探讨中医方药对应激状态下机体单核吞噬细胞系统功能的作用,国内尚乏报道。为此,本文初步研究了甘草水煎剂对应激状态下小鼠腹

英文摘要:

In this paper,we investigated the influence of the liquorice decoction on phagocytosis of peritoneal macrophages of mice being in a stressed state due to a stressor(cold,heat,starvation). The liquorice has been regarded as a Chinese traditional medicine with a reinforcing vital energy.The results obtained from the experiment showed that this phagocytosis in the normal mice can be inhibited by the liquorice decoction,whereas it can be enhanced in the stressed mice. The action of the liquorice decoction on phagocytosis mentioned above is closely related with the physiological stare of mice. In our experiment,manifestations of a decrease in resistance occurred apparentlyin all of the stressed mice,but none was found in the normal mice.The enhancement of liquorice decoedon in the former and its inhibition in the latter showed that the reinforcing action of the liquprice decoction reported by the Chinese traditional medicine is only suitable to cases with weak resistance,but not to the normal ones. Such a result may provide some experimental proof for the theory of"Reinforcement(Bu 补)for Deficiency(Xu 虚) only"as given in the Literature of TCM.

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