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张泰怀,蒋俊明.生脉注射液治疗感染性休克[J].中国中西医结合杂志,1983,(1):10-11,2
生脉注射液治疗感染性休克
Shengmai Injection in the Treatment of Infectious Shock
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DOI:
中文关键词:  生脉注射液  感染性休克  变形杆菌败血症  血管活性药物  综合措施  大肠杆菌  血压  休克型肺炎  患者  中毒性心肌炎
英文关键词:
基金项目:
作者单位
张泰怀 四川医学院温病理论研究室 
蒋俊明 四川医学院温病理论研究室 
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中文摘要:
      为了探索感染性休克新的治疗措施,我室应用生脉注射液治疗24例感染性休克患者,发现在稳定及回升血压、促进病情好转、改善全身机能状态等方面均有较好的疗效,报告如下。一般资料24例中,男性14例,女性10例。年龄最大71岁,最小18岁。原发病有:大肠杆菌败血症6例;金葡败血症1例;变形杆菌败血症1
英文摘要:
      This is a report of therapeutic efficacy of Shengraai injection in the treatment of 24 patients with clinically comfirmed infectious shock.Shengmai injection prescription prepared by t(?)e department of pharmacy of Sichuan Medical College is similar to the composition of an ancient TCM prescription.It includes:Panax ginseng 1gm; Liriope spicata 3.12gm;and Schisandra Chinensis 1.56gm.The injection was given intravenously 40-100ml per day for one or two days either singly or in combination with other medicine.Following medication,stabilization and increase of blood pressure as well as functional improvement of other organs were observed.Of all the patients,17 cases which had been irresponsive to vascular activators showed stabilization and elevation of blood pressure after the addition of Shengmai injection.In the remaining 7 cases in which Shengmai injection was given singly,similar results were obtained.Pharmaceutical studies revealed that the effects of Shengmai injection include:anti- inflammatory effect;anti-toxic effect;decrease of capillary permeability;enhancement of cell-mediated immunity; inhibition of IgE-mediated immunity;stimulation of adrenocortical function;elevation of hypoxic endurance; activation of reticulo-endothelial system;and effects on myocardiam and hemodynamics.The actions mentioned above will contribute to a further application of this injection in clinical practice.
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