| 于惠钦,张育轩.联苯双酯对慢性肝炎及肝硬变患者某些异常化验指标的疗效观察[J].中国中西医结合杂志,1983,(3):163-164,131 |
| 联苯双酯对慢性肝炎及肝硬变患者某些异常化验指标的疗效观察 |
| Effect of Biphenyl Dicarbosylate in Treating Some of the Abnormal Laboratory Findings in Patients with Chronic Hepatitis and Liver Cirrhosis |
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| DOI： |
| 中文关键词: 慢性肝炎 肝硬变 甲胎蛋白 疗效观察 慢性病毒性肝炎 血清蛋白电泳 胆红素 白蛋白 球蛋白 联苯双酯 |
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| 中文摘要: |
| 联苯双酯治疗慢性病毒性肝炎,临床已初步肯定其降血清谷丙转氮酶的近期疗效。为了进一步探讨该药治疗慢性肝炎及肝硬变的作用机理,在门诊选择具有某些异常化验指标(蛋白电泳、甲胎蛋白、胆红素)的慢性肝炎及肝硬变患者作为疗效观察对象。现报告如下。 |
| 英文摘要: |
| This paper is a preliminary report of the effect of biphenyl dicarbosylate on treating the abnormalities of serum protein electrophoresis,α-FP and bilirubin in patients with chronic persistent hepatitis,chronic active hepatitis and liver cirrhosis.A control group treated with western drugs of liver-protection nature was also installed.The result showed that the biphenyl diearbosylate was not only effective in lowering down the raised serum GPT but also quite effective in putting right the electrophoretie changes of serum protein,α-FP as well as bilirubin.The average value of albumin changed from 49.9% before treatment to 53.99% after treatment(P<0.01).In case of α-FP the pretreatmental value was 89.06ng/ml and the post treatmental value was 19.22ng/ml(P<0.001),while in the control group values of serum protein and α-FP before and after the treatment did not reveal much difference.As to the effect of biphenyl dicarbosytate on bilirubin,it was found among a series of 20 cases 80% was markedly effective, 5% was improving and 15% was noneffective.This apparently expiains biphenyl dicarbosylate was also effective in bringing down the elevated serum bilirubin.All the results observed support our original viewpoint regarding the action mechanism of biphenyl dicarbosylate,that is,in addition to inhibiting the elevation of serum GPT,it also exerts a protective function on liver and contributes to the recovery of the damaged liver cells. |
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