| 秦万章,章谷生,周才一,唐观甜,韩堃元,朱光斗.胶原病及其重叠胶原病活血化瘀治疗与免疫实验研究[J].中国中西医结合杂志,1983,(4):210-213,195 |
| 胶原病及其重叠胶原病活血化瘀治疗与免疫实验研究 |
| Combinative Study of Blood Stasis and Method of Activating Blood Circulation and Removing Stasis with Immunological Investigation in Collagen Diseases and Overlapping Collagen Diseases |
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| DOI： |
| 中文关键词: 胶原病 型胶原 实验研究 重叠综合征 活血化瘀治疗 免疫紊乱 免疫指标 硬皮病 实验室检查 测定结果 |
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| 中文摘要: |
| 胶原病或重叠胶原病临床上都有较多的血瘀见证,采用活血化瘀法获得一定疗效。为此,我们进行这组疾病免疫实验研究,对探讨血瘀本质及活血化瘀作用原理都有帮助。 |
| 英文摘要: |
| 275 patients with various collagen diseases and overlapping collagen diseases（OL）,including 128 systemic lupus erythematosus,30 discoid lupus erythematosus,43 scleroderma,21 dermatomyositis,16 OL of Ⅰ type,16 mixed connective tissue disease（MCTD）and 21 OL of Sj（?）gren’s syndrome were studied.There are quite a few common clinical symptoms of blood stasis in these cases（37.8-80%）,such as cyanosis of tongue,Raynaud’s phenomenon,skin induration,pathological,mass,arthralgia,disturbance of menstruation,etc.Immunological examinations,including antinuclear antibody,rheumatoid factor,anti- DNP antibody,immunoglobulins,complement（C3）,skin test（such as OT,SD-SK test and PHA test）,the total E rosette forming cell and active E rosette forming cell（T cell）,and sialic acid were determined, and abnormal results were obtained. 275 patients were treated with the method of activating blood circulation and removing stasis（ABC- RS）using traditional Chinese medicine（Tripterygium Wilfordii Hook F,Tripterygium hypoglarucum （Levl）Hutch,Salvia Miltiorrhiza etc.）with symptomatic improvement in different degrees. The results show that from the symptoms of blood stasis and disturbances of immunity,ABC-RS may be equally improved.We can conclude that from these findings,there is a close relation between abnormal immunological functions and symptoms of blood stasis in collagen diseases and OL. |
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