弦滑脉的血液动力学分析

作者	单位
陈德奎	上海市高血压研究所
沈家麒	上海市高血压研究所
陆华	上海市高血压研究所
邱慧丽	上海市高血压研究所
李惜惜	复旦大学
柳兆荣	复旦大学

摘要点击次数: 1644

全文下载次数: 984

中文摘要:

中医脉象研究从血液动力学的角度出发,用非线性弹性腔理论建立流体动力学的数学模式,导出脉图图形与血液动力学参数之间的定量关系式,从而对脉图的生理病理意义进行了探讨。本文通过临床分析定出滑脉、平脉与弦脉所对应的血液动力学参数的变化范围,最后通过动物实验,借助药物改变动物血

英文摘要:

Examination of the radial pulse has been one of the important items of clinical diagnosis in TCM.The physiological and pathological implications of the radial pulse have not been fully studied until recent years.We have reported the establishment of a mathematical model according to non-linear elastic chamber hypothesis and derivation of the relative equations for the stroke volume of the heart(SV),the total peripheral resistance(TPR)and arterial compliance(Co)from the pulse wave form by using strain gauge method and impedance rheogram. In this clinical study,28 normal pulse,32 slippery pulse of pregnancy,and 47 taut pulse of hypertension were investigated.A comparison between slippery pulse was classified according to hardness into three grades,namely 1,2 and 3 respectively.It was found that the predicrotic pulse wave of the taut pulse ascended with increasing hardness,whereas in the case of slippery pulse,the predicrotic pulse descended.The higher the taut pulse,the greater the increase of TPR.arterial elastic modulus and the decrease of the stroke volume.This turned out opposite in the case of slippery pulse. Animal experiment in dogs has demonstrated that infusion of nor-epinephrine,a vasoconstricting agent,induced a pulse pattern similar to taut pulse,while viscum coloratum,a vasodilating agent.induced a pulse pattern similar to slippery pulse.

关闭